INDUCTION OF PEROXISOMAL BETA-OXIDATION IN THE RAT-LIVER INVIVO AND INVITRO BY TETRAZOLE-SUBSTITUTED ACETOPHENONES - STRUCTURE ACTIVITY RELATIONSHIPS

被引：37

作者：

EACHO, PI ^{[1
]}

FOXWORTHY, PS ^{[1
]}

DILLARD, RD ^{[1
]}

WHITESITT, CA ^{[1
]}

HERRON, DK ^{[1
]}

MARSHALL, WS ^{[1
]}

机构：

[1] LILLY CORP CTR,INDIANAPOLIS,IN 46285

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1989年 / 100卷 / 01期

关键词：

D O I：

10.1016/0041-008X(89)90100-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：177 / 184

页数：8

共 27 条

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[2] LEUKOTRIENE RECEPTOR ANTAGONISTS .2. THE [[(TETRAZOL-5-YLARYL)OXY]METHYL]ACETOPHENONE DERIVATIVES
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[3] NEW TABLES FOR MULTIPLE COMPARISONS WITH CONTROL
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[4] EACHO PI, 1988, FASEB J, V2, pA1048
[5] HEPATIC PEROXISOMAL CHANGES INDUCED BY A TETRAZOLE-SUBSTITUTED ALKOXYACETOPHENONE IN RATS AND COMPARISON WITH OTHER SPECIES
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[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1986, 83 (03) : 430 - 437
[6] BIOCHEMICAL, HISTOLOGICAL, AND ULTRASTRUCTURAL-CHANGES IN RAT AND MOUSE-LIVER FOLLOWING THE ADMINISTRATION OF TRICHLOROETHYLENE - POSSIBLE RELEVANCE TO SPECIES-DIFFERENCES IN HEPATOCARCINOGENICITY
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[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1985, 79 (03) : 365 - 376
[7] THE SHORT-TERM AND LONG-TERM EFFECTS OF BEZAFIBRATE IN THE RAT
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STEGMEIER, K
[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1982, 386 (MAY) : 111 - 135
[8] FLEISCH JH, 1985, J PHARMACOL EXP THER, V233, P148
[9] INHIBITION OF HEPATIC FATTY-ACID OXIDATION AT CARNITINE PALMITOYLTRANSFERASE-I BY THE PEROXISOME PROLIFERATOR 2-HYDROXY-3-PROPYL-4-[6-(TETRAZOL-5-YL)HEXYLOXY]ACETOPHENONE
FOXWORTHY, PS
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[J]. BIOCHEMICAL JOURNAL, 1988, 252 (02) : 409 - 414
[10] FOXWORTHY PS, 1986, TOXICOL LETT, V30, P189

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