TNP-LPS INDUCES AN IGG ANTI-TNP IMMUNE-RESPONSE IN MICE

被引：27

作者：

HUMBERT, J

MOTTA, I

TRUFFABACHI, P

机构：

[1] Unité d'Immunophysiologie Moléculaire, ER N 232 CNRS, Département d'Immunologie

来源：

CELLULAR IMMUNOLOGY | 1979年 / 47卷 / 01期

关键词：

D O I：

10.1016/0008-8749(79)90330-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The trinitrophenylated derivatives of lipopolysaccharide (TNP-LPS) elicit a specific anti-TNP, thymus-independent immune response in mice. After a single injection of antigen, anti-TNP antibodies of IgM and IgG isotypes are detected at the cellular and at the humoral levels, in athymic nude mice as well as in conventional (C57B1/6 × DBA/2)F1 mice. The immune sera were resolved into IgM and IgG molecules by gel filtration; both fractions showed an anti-TNP activity, thus confirming the data obtained by the cellular analysis. © 1979.

引用

页码：211 / 217

页数：7

共 21 条

[1]

BASTEN A, 1973, CONTEMP TOPICS IMMUN, V2, P265

[2] CELL INTERACTION IN AN IMMUNE RESPONSE IN-VITRO - REQUIREMENT FOR THETA-CARRYING CELLS [J].