LOOK-BACK STUDY OF INFECTIVITY OF ANTI-HCV ELISA-POSITIVE BLOOD COMPONENTS

被引：55

作者：

VRIELINK, H

VANDERPOEL, CL

REESINK, HW

ZAAIJER, HL

SCHOLTEN, E

KREMER, LCM

CUYPERS, HTM

LELIE, PN

VANOERS, MHJ

机构：

[1] NETHERLANDS RED CROSS,BLOOD TRANSFUS SERV,CENT LAB,AMSTERDAM,NETHERLANDS

[2] UNIV AMSTERDAM,ACAD MED CTR,1105 AZ AMSTERDAM,NETHERLANDS

来源：

LANCET | 1995年 / 345卷 / 8942期

关键词：

D O I：

10.1016/S0140-6736(95)90063-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The infectivity of blood components from donors who were later found to be anti-HCV ELISA-positive was investigated in recipients who were enrolled in a look-back programme. Recipients received ELISA-positive blood components from donors who were PCR-positive and/or RIBA-2-positive (n=22, group A) or PCR-negative and indeterminate or negative on RIBA-2 (n=105, group B). 26 of 32 (81%) recipients of group A donors and none of 140 of group B were HCV-infected. All stored serum samples of previous donations (n=172) of group A donors were anti-HCV-positive in RIBA-3, indicating a chronic carrier state of HCV in these donors.

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页码：95 / 96

页数：2

相关论文

共 8 条

[1] LETS LOOK AT HUMAN-IMMUNODEFICIENCY-VIRUS LOOK-BACK BEFORE LEAPING INTO HEPATITIS-C VIRUS LOOK-BACK [J].

BUSCH, MP .

TRANSFUSION, 1991, 31 (07) :655-661

[2] STORAGE-CONDITIONS OF BLOOD-SAMPLES AND PRIMER SELECTION AFFECT THE YIELD OF CDNA POLYMERASE CHAIN-REACTION PRODUCTS OF HEPATITIS-C VIRUS [J].

CUYPERS, HTM ;

BRESTERS, D ;

WINKEL, IN ;

REESINK, HW ;

WEINER, AJ ;

HOUGHTON, M ;

VANDERPOEL, CL ;

LESLIE, PN .

JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (12) :3220-3224

[3] RECOMBINANT IMMUNOBLOT ASSAY FOR HEPATITIS-C VIRUS-ANTIBODY AS PREDICTOR OF INFECTIVITY [J].

EBELING, F ;

NAUKKARINEN, R ;

LEIKOLA, J .

LANCET, 1990, 335 (8695) :982-983

[4] IDENTIFICATION OF HIV-INFECTED TRANSFUSION RECIPIENTS - THE UTILITY OF CROSS-REFERENCING PREVIOUS DONOR RECORDS WITH AIDS CASE-REPORTS [J].

SAMSON, S ;

BUSCH, M ;

WARD, J ;

GARNER, J ;

SALK, S ;

FERNANDO, L ;

HOLLAND, P ;

RUTHERFORD, G ;

BENJAMIN, R ;

PERKINS, H .

TRANSFUSION, 1990, 30 (03) :214-218

[5] EVALUATION OF 3RD-GENERATION SCREENING AND CONFIRMATORY ASSAYS FOR HCV ANTIBODIES [J].

UYTTENDAELE, S ;

CLAEYS, H ;

MERTENS, W ;

VERHAERT, H ;

VERMYLEN, C .

VOX SANGUINIS, 1994, 66 (02) :122-129

[6]

VANDERPOEL C, 1991, TRANSFUSION, V31, P777

[7] CONFIRMATION OF HEPATITIS-C VIRUS-INFECTION BY NEW 4-ANTIGEN RECOMBINANT IMMUNOBLOT ASSAY [J].

VANDERPOEL, CL ;

CUYPERS, HTM ;

REESINK, HW ;

WEINER, AJ ;

QUAN, S ;

DINELLO, R ;

VANBOVEN, JJP ;

WINKEL, I ;

MULDERFOLKERTS, D ;

EXELOEHLERS, PJ ;

SCHAASBERG, W ;

LEENTVAARKUYPERS, A ;

POLITO, A ;

HOUGHTON, M ;

LELIE, PN .

LANCET, 1991, 337 (8737) :317-319

[8] CONFIRMATION OF HEPATITIS-C INFECTION - A COMPARISON OF 5 IMMUNOBLOT ASSAYS [J].

ZAAIJER, HL ;

VRIELINK, H ;

VANEXELOEHLERS, PJ ;

CUYPERS, HTM ;

LELIE, PN .

TRANSFUSION, 1994, 34 (07) :603-607