ENCEPHALITOGENIC PROTEIN - STRUCTURE

被引：69

作者：

KIBLER, RF

SHAPIRA, R

MCKNEALLY, S

JENKINS, J

SELDEN, P

CHOU, F

机构：

[1] Department of Medicine (Neurology), Emory University, Atlanta

来源：

SCIENCE | 1969年 / 164卷 / 3879期

关键词：

D O I：

10.1126/science.164.3879.577

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Amino acid sequences of encephalitogenic proteins from bovine cord and rabbit brain are reported. The bovine protein contains 45 residues. The rabbit protein is identical except for two isopolar substitutions, a dipeptide and amino acid deletion. Analysis of this protein and a 140-residue myelin basic protein indicates that the smaller protein is a portion of the larger encephalitogen. The larger myelin protein contains at least two encephalitogenic sites.

引用

页码：577 / +

页数：1

共 21 条

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[5] ALLERGIC ENCEPHALOMYELITIS - STRUCTURE OF ENCEPHALITOGENIC DETERMINANT
EYLAR, EH
HASHIM, GA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1968, 61 (02) : 644 - &
[6] KIBLER RF, 1968, FED PROC, V27, P464
[7] ISOLATION OF HIGHLY PURIFIED ENCEPHALITOGENIC PROTEIN FROM BOVINE CORD
KIBLER, RF
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[J]. NATURE, 1964, 204 (496) : 1273 - &
[8] KIBLER RF, 1968, J BIOL CHEM, V243, P281
[9] KIES MW, 1965, ANN NY ACAD SCI, V122, P148
[10] KIES MW, 1965, ANN NY ACAD SCI, V122, P161

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