THE EVIDENCE OF THYROLIBERIN TRIIODOTHYRONIN CONTROL OF TSH SECRETORY RESPONSE FROM HUMAN PERIPHERAL-BLOOD MONOCYTES CULTURED IN-VITRO

被引：15

作者：

KOMOROWSKI, J

STEPIEN, H

PAWLIKOWSKI, M

机构：

[1] Department of Endocrinology, The Medical University of Łódź, School of Medicine, 91-425 Łódź

来源：

NEUROPEPTIDES | 1993年 / 25卷 / 01期

关键词：

D O I：

10.1016/0143-4179(93)90065-I

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Immune system function has been shown to be under the influence of various neuromodulators and endocrine system peptides. This in vitro study describes the stimulatory effect of thyrotropin releasing hormone (thyroliberin, TRH) on thyrotropin (TSH) release from cultured human peripheral blood monocytes. The stimulatory effect of TRH on TSH release from monocytes is totally blocked by triiodothyronine (T3) administrations. These results indicate that TSH release from human monocytes is under the control of TRH/T3 mechanisms, similar to hypothalamic-pituitary-thyroid axis.

引用

页码：31 / 34

页数：4

共 23 条

[1] A MOLECULAR-BASIS FOR BIDIRECTIONAL COMMUNICATION BETWEEN THE IMMUNE AND NEURO-ENDOCRINE SYSTEMS [J].