IMPLANTS OF HETEROLOGOUS DEMINERALIZED BONE-MATRIX FOR INDUCTION OF POSTERIOR SPINAL-FUSION IN RATS

被引：57

作者：

GUIZZARDI, S ^{[1
]}

DISILVESTRE, M ^{[1
]}

SCANDROGLIO, R ^{[1
]}

RUGGERI, A ^{[1
]}

SAVINI, R ^{[1
]}

机构：

[1] UNIV PARMA,INST HISTOL,I-43100 PARMA,ITALY

来源：

SPINE | 1992年 / 17卷 / 06期

关键词：

DEMINERALIZED BONE MATRIX; SPINAL FUSION;

D O I：

10.1097/00007632-199206000-00010

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors tested the osteoinductive capacity of powdered heterologous (bovine) demineralized bone matrix in rats. The first part of the study concerned a monolateral posterior spinal implant after decortication of three vertebrae, using as a control area the animal's contralateral side, in which neither bone graft nor any other material were placed. In another group of rats, a comparative evaluation was made of powdered heterologous demineralized bone matrix and fresh autologous bone. In the same animal, autologous bone was implanted to realize a thoracic posterior fusion and demineralized bone matrix, to induce a posterior fusion in the lumbar area. All data obtained suggested a good osteoinductive activity of heterologous powdered demineralized bone matrix. The two posterior spinal fusions done in the same animal with heterologous demineralized bone matrix or autologous bone, respectively, had similar callus development and required the same time for formation.

引用

页码：701 / 707

页数：7

共 37 条

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