PROLONGATION OF RV-PA CONDUIT LIFE-SPAN BY PERCUTANEOUS STENT IMPLANTATION - INTERMEDIATE-TERM RESULTS

被引：117

作者：

POWELL, AJ

LOCK, JE

KEANE, JF

PERRY, SB

机构：

[1] HARVARD UNIV,CHILDRENS HOSP,SCH MED,DEPT CARDIOL,BOSTON,MA 02115

[2] HARVARD UNIV,CHILDRENS HOSP,SCH MED,DEPT MED,BOSTON,MA 02115

来源：

CIRCULATION | 1995年 / 92卷 / 11期

关键词：

STENTS; CATHETERIZATION; HEART DEFECTS; CONGENITAL; ANGIOPLASTY; PROSTHESIS;

D O I：

10.1161/01.CIR.92.11.3282

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background Right ventricle-to-pulmonary artery (RV-PA) homografts and bioprosthetic conduits are commonly used to palliate various types of complex congenital heart disease. These conduits frequently develop progressive obstruction and require surgical replacement. This report reviews our experience implanting balloon-expandable stents to relieve conduit obstruction and delay reoperation. Methods and Results A retrospective review identified 44 patients who underwent placement of 48 stents in obstructed RV-PA conduits. Median patient age was 6.9 years (range, 7 months to 30 years), and median follow-up time was 14.2 months (range, 0 to 48 months). Stent implantation initially decreased the RV-PA pressure gradient from 61.0+/-16.9 to 29.7+/-11.9 mm Hg (P less than or equal to.001) and the right ventricular-to-systemic arterial pressure ratio from 0.92+/-0.17 to 0.63+/-0.20 (P less than or equal to.001). The diameter of the stenotic region expanded from 9.3+/-3.5 to 12.3+/-3.3 mm in the anteroposterior view (P less than or equal to.001) and from 6.6+/-2.9 to 10.9+/-2.5 mm in the lateral view (P less than or equal to.001). During the follow-up period, 2 patients had their stents redilated, 7 had additional conduit stents deployed, and 14 underwent surgical replacement of their conduits. Actuarial freedom from conduit reoperation was 65% at 30 months postprocedure. Seven patients were found to have fractured stents on follow-up, suggesting an important role for external compressive forces in conduit failure. Recatheterization in 16 patients a median of 11.8 months (3 to 48 months) postprocedure demonstrated hemodynamic evidence of recurrent obstruction despite sustained enlargement at the previously stented sites. Complications included stent displacement (n=1), bacterial endocarditis (n=1), and false aneurysm formation (n=1). One patient died awaiting conduit replacement surgery. Conclusions Stent implantation in obstructed RV-PA conduits results in significant immediate hemodynamic and angiographic improvement. In a subgroup of patients, the procedure prolongs conduit life span by several years and increases the interval between conduit reoperations. Recurrent obstruction is caused by external compression and progressive stenosis outside the stented region.

引用

页码：3282 / 3288

页数：7

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