MODULATION OF MAMMALIAN POLYOL - NADP OXIDOREDUCTASE ACTIVITY BY ADP AND ATP

被引：19

作者：

CLEMENTS, RS

WINEGRAD, AI

机构：

[1] George S. Cox Institute Department, Medicine University of Pennsylvania, Philadelphia

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 36卷 / 06期

关键词：

D O I：

10.1016/0006-291X(69)90304-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The xylose-reducing activity of polyol:NADP oxidoreductases isolated and partially purified from rabbit lens, sciatic nerve, and pancreas were found to be stimulated by ATP and to be inhibited by ADP. With the lens enzyme these effects of ATP and ADP appear to be associated with changes in Vmax without significant changes in the Km's for xylose or NADPH. © 1969.

引用

页码：1006 / &

共 11 条

[1]

CLEMENTS RL, IN PRESS

[2]

DAVIS BJ, 1964, NY ACAD SCI, V121, P321

[3]

DAVIS BJ, 1964, ANN NY ACAD SCI, V121, P404

[4]

HAYMAN S, 1965, J BIOL CHEM, V240, P877

[5] ALDOSE REDUCTASE [J].