BLOCKADE BY CIMETIDINE OF THE EFFECTS OF HISTAMINE ON ADENYLATE-CYCLASE ACTIVITY, SPONTANEOUS RATE AND CONTRACTILITY IN THE DEVELOPING PRENATAL HEART

被引:26
作者
WOLLEMANN, M [1 ]
PAPP, JG [1 ]
机构
[1] ATTILA JOZSEF UNIV,SCH MED,DEPT PHARMACOL,H-6701 SZEGED,HUNGARY
来源
AGENTS AND ACTIONS | 1979年 / 9卷 / 01期
关键词
D O I
10.1007/BF02024094
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The results support the view that in man cardiac responsiveness to histamine appears at a very early stage of development. It might also be suggested that in human embryonic and foetal hearts the adenylate cyclase activating, positive chronotropic and ventricular inotropic effects of histamine are mediated via H2-type histaminergic receptors. © 1979 Birkhäuser-Verlag.
引用
收藏
页码:29 / 30
页数:2
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