NEW SYNTHESIS OF 1,2,4-TRIAZOLES AND 1,2,4-OXADIAZOLES

被引：83

作者：

LIN, YI

LANG, SA

LOVELL, MF

PERKINSON, NA

机构：

[1] American Cyanamid Company, Medical Research Division, New York, Pearl River

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 23期

关键词：

D O I：

10.1021/jo01337a031

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthesis of 1, 2, 4-triazoles and 1, 2, 4-oxadiazoles has been developed. N'-Acyl-N.N-dimethylamidines, which were prepared in excellent yields by reactions of amides with M-Y-dimethylalkan amide dimethyl acetals, reacted with hydrazines or hydroxylamine in acetic acid to give 1, 2, 4-triazoles or 1, 2, 4-oxadiazoles, respectively, in excellent yields. Copyright © 1979, American Chemical Society. All rights reserved.

引用

页码：4160 / 4164

页数：5

共 19 条

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