RISK-FACTORS OF NONMELANOMA SKIN-CANCER IN RAGUSA, SICILY - A CASE-CONTROL STUDY

被引:28
作者
GAFA, L [1 ]
FILIPPAZZO, MG [1 ]
TUMINO, R [1 ]
DARDANONI, G [1 ]
LANZARONE, F [1 ]
DARDANONI, L [1 ]
机构
[1] UNIV PALERMO,DIPARTIMENTO IGIENE & MICROBIOL,VIA VESPRO 133,I-90127 PALERMO,ITALY
关键词
Case-control study; Italy; nonmelanoma skin cancer; preventive measures;
D O I
10.1007/BF00054300
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A case-control study on 133 consecutive incident cases of nonmelanoma skin cancer registered by Cancer Registry of Ragusa (Sicily) was carried out in order to evaluate the correspondence between risk factors observed in other geographic areas with those of a Latin country with a strong solar exposure. A multivariate analysis showed that family history of skin cancer, cancer-related cutaneous diseases, fair skin color, residence more than 400 meters above sea level, and prolonged solar exposure without protection, significantly and independently increase the risk of skin cancer. Ease of suntanning was an important protective factor. Solar exposure was a stronger risk factor for squamous cell than for basal cell cancer. The results of the study enable us to identify a high risk group of people to whom simple methods of protection against solar exposure may be suggested to reduce the risk of skin cancer.
引用
收藏
页码:395 / 399
页数:5
相关论文
共 9 条
[1]  
Unna P.G., The Histopathology of the Diseases of the Skin, (1896)
[2]  
Frieben E., Demonstration eines Cancroids des rechtens Handdruckens, dass sich nach langdauernder Einvirkung von Roentgenstrahlen entwickelte hatte, Fortschr Rongenstrahl, 6, (1902)
[3]  
Bellini A., Dell'influenza degli agenti fisici e piu'particolarmente della luce sull'eziologia dell'epitelioma cutaneo, Giorn Ital Mal Ven e Pelle, 1, pp. 732-98, (1909)
[4]  
Cook J.W., Hieger I., Kennaway E.L., Et al., The production of cancer by pure hydrocarbons. Part I, Proc Roy Soc Lond, 3, pp. 455-84, (1932)
[5]  
Emmet A., Occupational skin cancer. A review, Journal of Occupational and Environmental Medicine, 17, pp. 44-9, (1975)
[6]  
Ada R.M., Occupational Skin Diseases, (1983)
[7]  
La Vecchia C., Decarli A., Cislaghi C., Franceschi S., Levi F., Tumori della cute ed esposizione al sole, Aggiorn del Med, 12, pp. 198-205, (1988)
[8]  
Dardanoni L., Gafa' L., Paterno' R., Pavone G., A case control study on lip cancer risk factors in Ragusa (Sicily), Int J Cancer, 34, pp. 355-6, (1984)
[9]  
Woolf B., On estimating the relation between blood group and disease, Annals of Human Genetics, 19, pp. 251-3, (1955)