MALIGNANT RHABDOID TUMOR OF THE LIVER - A CASE-REPORT

被引：26

作者：

FOSCHINI, MP

VANEYKEN, P

BROCK, PR

CASTEELSVANDAELE, M

DEVOS, R

DALCIN, P

VANDENBERGHE, H

DESMET, VJ

机构：

[1] UNIV ZIEKENHUIS SINT RAFAEL, DEPT PATHOL 2, HISTO CYTOCHEM LAB, MINDERBROEDERSSTR 12, B-3000 LOUVAIN, BELGIUM

[2] CATHOLIC UNIV LEUVEN, CTR HUMAN GENET, B-3000 LOUVAIN, BELGIUM

[3] UNIV ZIEKENHUIS GASTHUISBERG, DEPT PAEDIAT, LOUVAIN, BELGIUM

来源：

HISTOPATHOLOGY | 1992年 / 20卷 / 02期

关键词：

MALIGNANT RHABDOID TUMOR; LIVER; CYTOKERATIN; VIMENTIN;

D O I：

10.1111/j.1365-2559.1992.tb00946.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A case of primary malignant rhabdoid tumour of the liver occurring in a 5-month-old girl is reported. Histologically the neoplasm presented the 'typical' features as described in malignant rhabdoid tumour arising in the kidney. In addition, some areas of the tumour showed a 'pseudoglandular' growth pattern. Immunohistochemistry revealed the neoplastic cells to be intensively positive for vimentin and for cytokeratin 19. Variable immunoreactivity for cytokeratin polypeptides 7, 8 and 19 was also detected. On electronmicroscopy the neoplastic cells contained bundles of intermediate filaments, tonofilaments and intercellular junctions. These findings are suggestive of a primitive epithelial differentiation.

引用

页码：157 / 165

页数：9

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