Platelet degranulation induced by some contrast media is independent of their nonionic vs ionic nature

被引：8

作者：

Grabowski, EF ^{[1
]}

Jang, IK ^{[1
]}

Gold, H ^{[1
]}

Palacios, IF ^{[1
]}

Boor, SE ^{[1
]}

Rodino, LJ ^{[1
]}

Michelson, AD ^{[1
]}

机构：

[1] UNIV MASSACHUSETTS,MED CTR,WORCESTER,MA

来源：

ACTA RADIOLOGICA | 1995年 / 36卷

关键词：

contrast media; flow cytometry; platelet aggregation;

D O I：

10.1177/0284185195036S39921

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We confirm that the phenomenon of platelet degranulation exists for both iohexol and diatrizoate, as reported earlier. In contrast to previous conclusions, however, we have determined that the degranulation is independent of the nonionic vs. ionic nature of the media per se, since degranulation was neither seen with nonionic iodixanol nor ionic ioxaglate. The degranulation, further, does not significantly augment platelet function, as measured by flowing whole blood platelet aggregometry.

引用

页码：182 / 184

页数：3

共 12 条

[1] PROFOUND PLATELET DEGRANULATION IS AN IMPORTANT SIDE-EFFECT OF SOME TYPES OF CONTRAST-MEDIA USED IN INTERVENTIONAL CARDIOLOGY [J].