AMMONIA DETOXICATION BY PYRROLIDONECARBOXILATE-ARGININE MIXTURE

被引:4
作者
DIROSA, M
机构
[1] Institute of Pharmacology, School of Medicine, University of Naples, Naples, via Constantinopoli
关键词
D O I
10.1016/0006-2952(68)90244-X
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The protective effect of pyrrolidonecarboxilate, arginine and their mixture against acute ammonia intoxication by an ld50 of ammonium acetate has been investigated in rats. Evaluation of the efficacy of the different treatments has been done on the basis of mortality as well as of blood ammonia and urea levels. Pyrrolidonecarboxilatearginine mixture was the most effective treatment in acute ammonia intoxication: possible mechanism of action is formulated. © 1968.
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页码:351 / &
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