IMMUNIZATION AGAINST EAST COAST FEVER USING TICK INFECTIONS AND CHLORTETRACYCLINE

被引：7

作者：

JARRETT, WFH

PIRIE, HM

SHARP, NCC

机构：

[1] Department of Experimental Veterinary Medicine, University of Glasgow Veterinary School, Glasgow, Scotland, Bearsden Road

来源：

EXPERIMENTAL PARASITOLOGY | 1969年 / 24卷 / 02期

关键词：

Chlortetracycline in immunization against Theileria parva; East Coast Fever immunization against; Immunity to Theileria parva; Theileria parva immunization against;

D O I：

10.1016/0014-4894(69)90151-9

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Five groups of cattle were infected with East Coast Fever. Four groups were treated with chlortetracycline from the day before ticks were put on the animals' ears. Treatment was continued until days 8, 16, 24, and 32 in respective groups. A growth curve was constructed for the development of Theileria parva (Muguga) as influenced by chlortetracycline. Treated groups were reinfected on day 70, and proved to be immune to the 10-tick challenge used. From these results it was concluded that the development of 109 macroschizonts between 16 and 21 days after infection with ten ticks is capable of producing an acceptable degree of immunity. © 1969.

引用

页码：147 / &