A CHIMERIC EGF-R-NEU PROTO-ONCOGENE ALLOWS EGF TO REGULATE NEU TYROSINE KINASE AND CELL-TRANSFORMATION

被引：98

作者：

LEHVASLAIHO, H ^{[1
]}

LEHTOLA, L ^{[1
]}

SISTONEN, L ^{[1
]}

ALITALO, K ^{[1
]}

机构：

[1] UNIV HELSINKI,TRANSPLANTAT LAB,SF-00290 HELSINKI 29,FINLAND

来源：

EMBO JOURNAL | 1989年 / 8卷 / 01期

关键词：

D O I：

10.1002/j.1460-2075.1989.tb03360.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：159 / 166

页数：8

共 48 条

[1] INCREASED TYROSINE KINASE-ACTIVITY ASSOCIATED WITH THE PROTEIN ENCODED BY THE ACTIVATED NEU ONCOGENE
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[3] MULTIPLE INDEPENDENT ACTIVATIONS OF THE NEU ONCOGENE BY A POINT MUTATION ALTERING THE TRANSMEMBRANE DOMAIN OF P185
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[5] HIGH-AFFINITY INTERLEUKIN 2 BINDING BY AN ONCOGENIC HYBRID INTERLEUKIN-2 - EPIDERMAL GROWTH-FACTOR RECEPTOR MOLECULE
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[6] TYROSINE KINASE RECEPTOR WITH EXTENSIVE HOMOLOGY TO EGF RECEPTOR SHARES CHROMOSOMAL LOCATION WITH NEU ONCOGENE
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YANGFENG, TL
LIAO, YC
CHEN, E
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[7] OVEREXPRESSION OF THE HUMAN EGF RECEPTOR CONFERS AN EGF-DEPENDENT TRANSFORMED PHENOTYPE TO NIH 3T3 CELLS
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ULLRICH, A
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[J]. CELL, 1987, 51 (06) : 1063 - 1070
[8] ERBB-2 IS A POTENT ONCOGENE WHEN OVEREXPRESSED IN NIH/3T3 CELLS
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AARONSON, SA
[J]. SCIENCE, 1987, 237 (4811) : 178 - 182
[9] IN-VITRO CULTIVATION OF HUMAN TUMORS - ESTABLISHMENT OF CELL LINES DERIVED FROM A SERIES OF SOLID TUMORS
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PARKS, WP
[J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1973, 51 (05) : 1417 - 1423
[10] SV40-TRANSFORMED SIMIAN CELLS SUPPORT THE REPLICATION OF EARLY SV40 MUTANTS
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[J]. CELL, 1981, 23 (01) : 175 - 182

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