METASTATIC CARCINOMA OF THE PENIS - COMPLETE REMISSION AFTER HIGH-DOSE METHOTREXATE CHEMOTHERAPY

被引：23

作者：

GARNICK, MB ^{[1
]}

SKARIN, AT ^{[1
]}

STEELE, GD ^{[1
]}

机构：

[1] PETER BENT BRIGHAM HOSP,DEPT SURG,BOSTON,MA 02115

来源：

JOURNAL OF UROLOGY | 1979年 / 122卷 / 02期

关键词：

D O I：

10.1016/S0022-5347(17)56360-0

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A case of extensive metastatic epidermoid carcinoma of the penis is reported. Disseminated disease developed after penectomy and lymphadenectomy and it continued to progress while the patient received radiation therapy. Chemotherapy with high dose methotrexate followed by citrovorum factor rescue was instituted. After completion of 10 weekly cycles of treatment there was biopsy-proved complete regression of all lesions, which lasted 9 months when the patient suddenly died of pneumonia completely unrelated to the tumor or chemotherapy treatment. This chemotherapeutic approach deserves additional trial in patients with advanced stages of penile carcinoma.

引用

页码：265 / 266

页数：2

共 9 条

[1] CARCINOMA OF PENIS [J].

BAKER, BH ;

SPRATT, JS ;

PEREZMESA, C ;

WATSON, FR ;

LEDUC, RJ .

JOURNAL OF UROLOGY, 1976, 116 (04) :458-461

[2]

DEKERNIO.JB, 1973, CANCER, V32, P1256, DOI 10.1002/1097-0142(197311)32:5<1256::AID-CNCR2820320534>3.0.CO

[3]

2-G

[4]

DEKERNION JB, 1978, GENITOURINARY CANCER, P494

[5] BLEOMYCIN TREATMENT OF TUMORS OF PENIS SCROTUM [J].

ICHIKAW, T ;

NAKANO, I ;

HIROKAWA, I .

JOURNAL OF UROLOGY, 1969, 102 (06) :699-&

[6]

MILLS EED, 1972, S AFR MED J, V46, P398

[7]

PITMAN SW, 1977, CANCER TREAT REP, V61, P695

[8]

SKARIN AT, 1977, BLOOD, V50, P1039

[9] BLEOMYCIN, AN ANTITUMOR ANTIBIOTIC - CLINICAL EXPERIENCE IN 274 PATIENTS [J].

YAGODA, A ;

TAN, CTC ;

YOUNG, C ;

SMITH, JR ;

ETCUBANAS, E ;

KRAKOFF, IH ;

LAMONTE, C ;

MUKHERJI, B .

ANNALS OF INTERNAL MEDICINE, 1972, 77 (06) :861-+

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