POOR DEVELOPMENT OF OUTER DENSE FIBERS AS A MAJOR CAUSE OF TAIL ABNORMALITIES IN THE SPERMATOZOA OF ASTHENOTERATOZOOSPERMIC MEN

被引：54

作者：

HAIDL, G

BECKER, A

HENKEL, R

机构：

[1] Department of Dermatology, Heinrich Heine University, Düsseldorf

[2] Centre of Dermatology and Andrology, Justus Liebig University, D-6300 Giessen

来源：

HUMAN REPRODUCTION | 1991年 / 6卷 / 10期

关键词：

FLAGELLAR DEFECTS; OUTER DENSE FIBERS; SHAFT DISTURBANCE; SPERM MOTILITY;

D O I：

10.1093/oxfordjournals.humrep.a137283

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

For a reasonable analysis of sperm motility, consideration should be given to the morphology of the flagellum. Among various tail disturbances, the present paper describes a structural shaft defect that is characterized by variations in diameter, poor outline and/or lacking endpiece. Electron microscopical examinations, especially the negative staining technique, have shown that in addition to membrane alterations there is one essential cause for the limited extension of the outer dense fibres. This disturbance may be of genetic origin or due to toxic or inflammatory influences. Further molecular biological studies are required to detect the actual cause of this defect, for which there is so far no adequate therapy.

引用

页码：1431 / 1438

页数：8

共 41 条

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