NEW ANTITUMOR PRINCIPLES, CASEARINS-A-F, FOR CASEARIA-SYLVESTRIS SW (FLACOURTIACEAE)

被引:88
作者
ITOKAWA, H
TOTSUKA, N
MORITA, H
TAKEYA, K
IITAKA, Y
SCHENKEL, EP
MOTIDOME, M
机构
[1] TEIKYO UNIV, FAC MED, HACHIOJI, TOKYO 19203, JAPAN
[2] UNIV FED RIO GRANDE SUL, FAC FARM, BR-90000 PORTO ALEGRE, RS, BRAZIL
[3] UNIV SAO PAULO, INST QUIM, SAO PAULO, BRAZIL
关键词
CASEARIN; CASEARINS-A-F; CASEARIA-SYLVESTRIS; FLACOURTIACEAE; ANTITUMOR PRINCIPLE; CLERODANE DITERPENE; SARCOMA; 180A; V-79; CELL; X-RAY ANALYSIS;
D O I
10.1248/cpb.38.3384
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
New antitumor clerodane diterpenes, named casearins A-F, have been isolated from the leaves of Casearia sylvestris Sw. (Flacourtiaceae). These structures have been completely elucidated by two dimensional nuclear magnetic resonance, circular dichroism spectroscopy, X-ray analysis, and chemical evidences.
引用
收藏
页码:3384 / 3388
页数:5
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