EFFECT OF INTRAVENOUS GLIBORNURIDE AND TOLBUTAMIDE ON MYOCARDIAL-CONTRACTILITY

被引：2

作者：

DUBACH, UC

BURCKHARDT, D

RAEDER, EA

FORGO, I

AMREIN, R

BUCKERT, A

机构：

[1] Department of Medicine, Kantonsspital Basel, Basel

来源：

CARDIOLOGY | 1979年 / 64卷 / 04期

关键词：

Glibornuride; Healthy volunteers; I.v; application; Myocardial contractility; Sulplionylureas; Tolbutamide;

D O I：

10.1159/000170617

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The acute effects of therapeutic doses of intravenous tolbutamide and glibornuride on the systolic time intervals (QS2c, LVETC, PEPC and PEP/LVET) were examined in 5 healthy volunteers. Blood sugar was maintained constant throughout the study. No significant changes of these intervals as well as of heart rate and blood pressure were observed. Therefore, it is concluded that tolbutamide and glibornuride have no acute positive inotropic action. © 1979 S. Karger AG, Basel.

引用

页码：208 / 214

页数：7

共 11 条

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[2]

CROCKETT S, 1973, DIABETES, V22, P1

[3]

EPSTEIN SE, 1972, CONTROVERSIES CLIN P

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