SOMATIC MUTATION AND MEMORY

被引：37

作者：

BEREK, C

机构：

[1] Deutsches RheumaForschungsZentrum, Berlin

来源：

CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 02期

关键词：

D O I：

10.1016/0952-7915(93)90007-F

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The germinal center plays a crucial role in the development of the memory B cell. The repertoire of the antigen-specific B cell is shaped in this microenvironment. Self-specific B cells escaping normal regulation may develop into high affinity pathogenic Ig-producing cells.

引用

页码：218 / 222

页数：5

共 35 条

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