SPINDLE-SHAPED APPENDAGES OF IIIAB-PYRAMIDS FILLED WITH LIPOFUSCIN - STRIKING PATHOLOGICAL CHANGE OF THE SENESCENT HUMAN ISOCORTEX

被引:33
作者
BRAAK, H
机构
[1] Anatomisches Institut der Universität Kiel, Kiel
关键词
Ageing; Isocortex; Lipopigments; Man; Pyramidal cells;
D O I
10.1007/BF00690844
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Brains from 30 mentally normal men, ranging in age from 18-90 years, were studied to assess the occurrence and development of lipofuscin-filled spindle-shaped appendages of pyramidal cell of the isocortex; these can generally be encountered in the senescent brain within layer IIIab. The number of pigmented spindles was determined in a circumscribed part of a prefrontal area revealing a close association of this conspicuous pathological alteration with growing age. © 1979 Springer-Verlag.
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页码:197 / 202
页数:6
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