HETEROCYCLIC-COMPOUNDS WITH A BRIDGEHEAD NITROGEN ATOM - SYNTHESIS IN THE IMIDAZO[1,2-C]QUINAZOLINE SERIES

被引：14

作者：

GUEIFFIER, A

VIOLS, H

CHAPAT, JP

CHAVIGNON, O

TEULADE, JC

DAUPHIN, G

机构：

[1] DEPT PHARMACOCHIM,CHIM ORGAN PHARMACEUT LAB,UER PHARM,F-63001 CLERMONT FERRAND,FRANCE

[2] LAB CHIM ORGAN BIOL,CNRS,UA 485,F-63170 CLERMONT FERRAND,FRANCE

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 02期

关键词：

D O I：

10.1002/jhet.5570270259

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The structures of imidazo[1,2‐c]quinazolines were reexaminated and established by spectroscopic studies with the aid of high‐field 1H and 13C nmr and mass spectra. In acidic media, 3 reacts to give the products of electrophilic substitution reaction and ring opening compound 5, leading to the imidazo[1,2‐c]benzo[e]‐[1,2,3]triazine ring. Copyright © 1990 Journal of Heterocyclic Chemistry

引用

页码：421 / 425

页数：5

共 27 条

[1]

ABIGNENTE E, 1977, FARMACO-ED SCI, V32, P735

[2] THEORETICAL APPROACH TO CHEMICAL REACTIVITY OF AZAINDENES - 2-IMIDAZO[1,2]AZINES [J].

ARRIAU, J ;

CHALVET, O ;

DARGELOS, A ;

MAURY, G .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1974, 11 (06) :1013-1016

[3]

BAX A, 1982, 2 DIMENSIONAL NMR LI, pCH2

[4]

CARDELLINI M, 1975, FARMACO-ED SCI, V30, P536

[5]

CLAUDI F, 1974, J ORG CHEM, V30, P3508

[6] NOVEL ONE-POT SYNTHESIS OF 4-AMINOQUINAZOLINES [J].

FOSTER, CH ;

ELAM, EU .

JOURNAL OF ORGANIC CHEMISTRY, 1976, 41 (15) :2646-2647

[7]

FRANCHETTI P, 1970, J HETEROCYCLIC CHEM, V7, P1295

[8]

GRASSY G, 1985, EUR J MED CHEM, V20, P501

[9]

HASHIMOTO Y, 1982, J AM CHEM SOC, V104, P7637

[10] INTERMEDIATES IN DIMROTH REARRANGEMENT OF IMIDAZO(1,2-A)PYRIDINES [J].

JACQUIER, R ;

LOPEZ, H ;

MAURY, G .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1973, 10 (05) :755-762

← 1 2 3 →