NUCLEOTIDE-SEQUENCES OF YEAST GENES FOR TRANSFER-RNA 2SER, TRANSFER-RNA 1VAL - HOMOLOGY BLOCKS OCCUR IN THE VICINITY OF DIFFERENT TRANSFER-RNA GENES

被引：21

作者：

BAKER, RE ^{[1
]}

EIGEL, A ^{[1
]}

VOGTEL, D ^{[1
]}

FELDMANN, H ^{[1
]}

机构：

[1] UNIV MUNICH, INST PHYSIOL CHEM PHYS BIOCHEM & ZELLBIOL, D-8000 MUNICH 2, FED REP GER

来源：

EMBO JOURNAL | 1982年 / 1卷 / 03期

关键词：

D O I：

10.1002/j.1460-2075.1982.tb01162.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three members of a collection of pBR322-yeast DNA recombinant plasmids containing yeast tRNA genes were analyzed and sequenced. Each plasmid carries a single tRNA gene: pY44, .**GRAPHIC**. pY41, .**GRAPHIC**. pY7, .**GRAPHIC**. All 3 genes are intronless and terminate in a cluster of Ts in the non-coding strand. The sequence information here and previously determined sequences allow an extensive comparison of the regions flanking several yeast tRNA genes. This analysis has revealed novel features in tRNA gene arrangement. Blocks of homology in the flanking regions were found between the tRNA genes of an isoacceptor family but, more interestingly, also between genes coding for tRNAs of different amino-acid specificities. Particularly, 3 examples are discussed in which sequence elements in the neighborhood of different tRNA genes were conserved to a high degree and over long distances.

引用

页码：291 / 295

页数：5

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