INCORPORATION AND REMOVAL OF LARGE AMOUNTS OF STRONTIUM BY PHYSIOLOGIC MECHANISMS IN MINERALIZED TISSUES OF RAT

被引：37

作者：

JOHNSON, AR

ARMSTRONG, WD

SINGER, L

机构：

[1] Department of Biochemistry, University of Minnesota, Minneapolis, 55455, Minnesota

来源：

CALCIFIED TISSUE RESEARCH | 1968年 / 2卷 / 03期

关键词：

Boen; Metabolism; Rats; Strontium; Tooth;

D O I：

10.1007/BF02279212

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The incorporation and removal of strontium from the bones and teeth of rats under conditions of low and high dietary levels of strontium were investigated. In an otherwise satisfactory diet, an amount of strontium equimolar to that of calcium seriously debilitates the young growing rat and may culminate in death. The pathology due to strontium was found by the methods used only in the hard tissues. The excess osteoid formed originally in the presence of large amounts of dietary strontium is removed during a subsequent period of feeding on a low strontium regimen. Strontium removal from participation in physiologic processes appears to be of two types, (a) excretion from the body, and (b) incarceration within the hard tissues. The translocation of strontium to the incisor teeth has been demonstrated. Differences of sodium and potassium contents of the hemi-mandibulae of the experimental and control groups were also observed. © 1968 Springer-Verlag.

引用

页码：242 / +

页数：1

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