EFFECTS OF VAGOTOMY ON GASTRIC MUCOSA OF RAT

被引:36
作者
CREAN, GP
GUNN, AA
RUMSEY, RDE
机构
[1] The Medical Research Council Endocrinology Research Unit, The University of Edinburgh
[2] The Surgical Unit, Bangour General Hospital, Broxburn
[3] The Gastrointestinal Centre, Southern General Hospital, Glasgow, Scotland
关键词
Gastric mucosa; Parietal cells; Peptic cells; Pyloroplasty; Stomach; Vagotomy;
D O I
10.3109/00365526909180653
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
In order to determine the effects of vagotomy on the gastric mucosa, the operations of pyloroplasty and vagotomy, pyloroplasty alone, and a sham operation were carried out in rats, and the parietal and peptic cell populations of the stomach were estimated in each animal. From the differences detected between the three groups it was concluded that vagotomy significantly reduced the average number of peptic cells per unit area of the mucosa (33 %), the total peptic cell population (34 %), and the height of the mucosa (19 %). Pyloroplasty alone did not exert any significant effects although it tended to reduce the total parietal cell population. © 1969 Informa UK Ltd.
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页码:675 / &
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