PRODUCTION OF PROTEIN HC BY HUMAN FETAL LIVER EXPLANTS

被引:43
作者
TEJLER, L
ERIKSSON, S
GRUBB, A
ASTEDT, B
机构
[1] UNIV LUND,MALMO GEN HOSP,DEPT MED,S-21401 MALMO,SWEDEN
[2] UNIV LUND,MALMO GEN HOSP,DEPT OBSTET & GYNECOL,S-21401 MALMO,SWEDEN
关键词
D O I
10.1016/0304-4165(78)90380-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Human fetal lever explants were found to secrete protein HC into the medium in molar amounts comparable to those of albumin, α1-antitrypsin and orosomucoid. Incorporation of a radioactive amino acid from the medium into the secreted protein HC demonstrated de novo synthesis. The secreted protein HC had the same size and electrophoretic mobility as protein HC of plasma and urine and gave a reaction of immunochemical identity with the protein in these biological fluids. © 1978.
引用
收藏
页码:506 / 514
页数:9
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