ANTIBODIES TO VARICELLA-ZOSTER VIRUS GLYCOPROTEIN-I, GLYCOPROTEIN-II, AND GLYCOPROTEIN-III IN LEUKEMIC AND HEALTHY-CHILDREN

被引：22

作者：

LARUSSA, PS ^{[1
]}

GERSHON, AA ^{[1
]}

STEINBERG, SP ^{[1
]}

CHARTRAND, SA ^{[1
]}

机构：

[1] CREIGHTON UNIV,DEPT PEDIAT,OMAHA,NE 68178

来源：

JOURNAL OF INFECTIOUS DISEASES | 1990年 / 162卷 / 03期

关键词：

D O I：

10.1093/infdis/162.1.627

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Adot ELISA was used to analyze the antibody response to varicella-zoster virus glycoproteins I, II, and 1lI in leukemic and healthy children who either developed natural varicella or received the live attenuated varicella vaccine. Both groups of children showed an antibody response to these viral glycoproteins. The antibody response to all three glycoproteins showed excellent persistence over the 3-year period of study. None of the glycoproteins provoked an antibody response that could be shown to correlate with protection from breakthrough varicella after household exposure chickenpox or from zoster in leukemic vaccinees. © 1990, by The University of Chicago.

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页码：627 / 633

页数：7

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