Young Wistar rats developed a fulminant infection when inoculated with the rodent malaria parasite Plasmodium berghei. Rats that died during the infection exhibited a progressive paralysis of the extremities. a rapidly decreasing body temperature and minute haemorrhages in the brain. Increasing the level of protein in the diet from 4 to 8 and 16% was accompanied by an increase in morbidity and mortality from 15 to 40 and 90% respectively on day 6 of the infection. Increasing the level of dietary protein also increased the reticulocyte count of the peripheral blood in infected and non-infected rats. The attenuation of the cerebral syndrome in rats fed a diet low in protein may be related to changes in erythropoiesis or to changes in immune reactivity.
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UNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLANDUNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLAND
EDIRISINGHE, JS
FERN, EB
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UNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLANDUNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLAND
FERN, EB
TARGETT, GAT
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UNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLANDUNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLAND
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UNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLANDUNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLAND
EDIRISINGHE, JS
FERN, EB
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UNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLANDUNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLAND
FERN, EB
TARGETT, GAT
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h-index: 0
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UNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLANDUNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PROTOZOOL,LONDON WC1E 7HT,ENGLAND