BIOSYNTHESIS OF 18-HYDROXYTESTOSTERONE IN HUMAN FOETAL LIVER

被引：22

作者：

LISBOA, BP

GUSTAFSSON, JA

机构：

[1] Hormonlaboretoriet, Karolinska Sjukhuset, Stockholm

[2] Kemiska Institutionen, Karolinska Institutet, Stockholm, S-10401

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1969年 / 9卷 / 03期

关键词：

D O I：

10.1111/j.1432-1033.1969.tb00622.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

After incubation of testosterone with 105 000 X g microsomes of human foetal liver, a C19 steroid with a 3‐oxo‐Δ4‐structure was isolated by ascending one‐dimensional thin‐layer chromatography. Gas chromatography‐mass spectrometry revealed that the compound was identical with 18‐hydroxytestosterone. The significance of this finding in relation to earlier reports of 18‐hydroxylated steroids in human urine is discussed. Copyright © 1969, Wiley Blackwell. All rights reserved

引用

页码：402 / +

页数：1

共 26 条

[1] THE BIOLOGICAL HYDROXYLATION OF 9-ALPHA-FLUOROANDROSTENEDIONE [J].