DISRUPTION OF THE SACCHAROMYCES-CEREVISIAE GENE FOR NADPH-CYTOCHROME-P450 REDUCTASE CAUSES INCREASED SENSITIVITY TO KETOCONAZOLE

被引：56

作者：

SUTTER, TR

LOPER, JC

机构：

[1] UNIV CINCINNATI,COLL MED,DEPT MOLEC GENET BIOCHEM & MICROBIOL,CINCINNATI,OH 45267

[2] UNIV CINCINNATI,COLL MED,DEPT ENVIRONM HLTH,CINCINNATI,OH 45267

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1989年 / 160卷 / 03期

关键词：

D O I：

10.1016/S0006-291X(89)80139-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1257 / 1266

页数：10

共 20 条

[1]

ANDERSON TG, 1970, MANUAL CLIN MICROBIO, P305

[2]

BLACK SD, 1987, ADV ENZYMOL RAMB, V60, P35

[3]

BROACH JR, 1979, GENE, V8, P121, DOI 10.1016/0378-1119(79)90012-X

[4] ISOLATION OF THE CANDIDA-TROPICALIS GENE FOR P450 LANOSTEROL DEMETHYLASE AND ITS EXPRESSION IN SACCHAROMYCES-CEREVISIAE [J].

CHEN, C ;

TURI, TG ;

SANGLARD, D ;

LOPER, JC .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 146 (03) :1311-1317

[5] PRIMARY STRUCTURE OF THE CYTOCHROME-P450 LANOSTEROL 14-ALPHA-DEMETHYLASE GENE FROM CANDIDA-TROPICALIS [J].

CHEN, C ;

KALB, VF ;

TURI, TG ;

LOPER, JC .

DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY, 1988, 7 (09) :617-626

[6] A SINGLE AMINO-ACID SUBSTITUTION CONVERTS CYTOCHROME-P450(14DM) TO AN INACTIVE FORM, CYTOCHROME-P450(SG1) - COMPLETE PRIMARY STRUCTURES DEDUCED FROM CLONED DNAS [J].

ISHIDA, N ;

AOYAMA, Y ;

HATANAKA, R ;

OYAMA, Y ;

IMAJO, S ;

ISHIGURO, M ;

OSHIMA, T ;

NAKAZATO, H ;

NOGUCHI, T ;

MAITRA, US ;

MOHAN, VP ;

SPRINSON, DB ;

YOSHIDA, Y .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 155 (01) :317-323

[7] PRIMARY STRUCTURE OF THE P450 LANOSTEROL DEMETHYLASE GENE FROM SACCHAROMYCES-CEREVISIAE [J].

KALB, VF ;

WOODS, CW ;

TURI, TG ;

DEY, CR ;

SUTTER, TR ;

LOPER, JC .

DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY, 1987, 6 (06) :529-537

[8] ISOLATION OF A CYTOCHROME-P-450 STRUCTURAL GENE FROM SACCHAROMYCES-CEREVISIAE [J].

KALB, VF ;

LOPER, JC ;

DEY, CR ;

WOODS, CW ;

SUTTER, TR .

GENE, 1986, 45 (03) :237-245

[9] CONVENIENT PROCEDURE FOR THE ISOLATION OF HIGHLY ENRICHED, CYTOCHROME-P-450-CONTAINING MICROSOMAL FRACTION FROM CANDIDA-TROPICALIS [J].

KAPPELI, O ;

SAUER, M ;

FIECHTER, A .

ANALYTICAL BIOCHEMISTRY, 1982, 126 (01) :179-182

[10] GENE ENGINEERING IN YEAST FOR BIODEGRADATION - IMMUNOLOGICAL CROSS-REACTIVITY AMONG CYTOCHROME-P-450 SYSTEM PROTEINS OF SACCHAROMYCES-CEREVISIAE AND CANDIDA-TROPICALIS [J].

LOPER, JC ;

CHEN, C ;

DEY, CR .

HAZARDOUS WASTE & HAZARDOUS MATERIALS, 1985, 2 (02) :131-141

← 1 2 →