SYNTHESIS AND PSYCHOTROPIC PROPERTIES OF 1-TRIORGANYLSILOXY-GERMATRANES AND 1-TRIORGANYLGERMOXY-GERMATRANES

被引：18

作者：

LUKEVICS, E

IGNATOVICH, L

SHILINA, N

GERMANE, S

机构：

[1] Institute of Organic Synthesis, Latvian Academy of Sciences, Riga, 226006

来源：

APPLIED ORGANOMETALLIC CHEMISTRY | 1992年 / 6卷 / 03期

关键词：

PHENYLSILOXYGERMATRANES; THIENYLSILOXYGERMTRANES; TRIPHENYLGERMOXYGERMATRANE; TOXICITY; PSYCHOTROPIC ACTIVITY;

D O I：

10.1002/aoc.590060303

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Triorganylsiloxy- and triorganylgermoxygermatranes have been prepared by the interaction of the easily available 1-hydroxygermatrane with various hetaryl-silanes and -germanes. The compounds were of the general structure: [GRAPHICS] M = Si; X = S, CH = CH (viz. phenyl); n = 0, 1, 2 M = Ge; X = CH = CH (viz. phenyl); n = 0 All siloxy- and germoxy-germatranes obtained were subjected to psychotropic assays. Some of phenylsiloxygermatranes are effective for memory enhancement (inhibition of retrogradal amnesia by triphenylsiloxygermatrane was 80%).

引用

页码：261 / 266

页数：6

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