DNA-PORPHYRIN INTERACTIONS PROBED BY INDUCED CD SPECTROSCOPY

被引：75

作者：

KURODA, R

TANAKA, H

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 13期

关键词：

D O I：

10.1039/c39940001575

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Detailed analysis by induced CD spectroscopy has revealed that the manganese porphyrin, Mn(tmpyp), binds the major groove of AT or GC sequences in DNA, as well as the reported minor groove of AT sequences, with a preference that depends on the porphyrin to DNA base-pair molar ratio.

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页码：1575 / 1576

页数：2

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