FAMILIAL TRANSITIONAL-CELL CARCINOMA AND THE LYNCH SYNDROME .2.

被引：10

作者：

GREENLAND, JE ^{[1
]}

WESTON, PMT ^{[1
]}

WALLACE, DMA ^{[1
]}

机构：

[1] QUEEN ELIZABETH HOSP,DEPT UROL,BIRMINGHAM B15 2TH,W MIDLANDS,ENGLAND

来源：

BRITISH JOURNAL OF UROLOGY | 1993年 / 72卷 / 02期

关键词：

D O I：

10.1111/j.1464-410X.1993.tb00683.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A family is presented in which 4 male siblings developed transitional cell carcinoma (TCC). Four upper tract tumours occurred in 3 and in the fourth the tumour was intravesical. Two of these patients also had colorectal adenocarcinoma. There were 2 other relatives in the pedigree with large bowel cancer. It is suggested that this is an example of Lynch Syndrome II, a hereditary non-polyposis colorectal cancer with extracolonic cancer sites. The implications regarding the screening, surveillance and detection of possible carrier status in healthy relatives is discussed.

引用

页码：177 / 180

页数：4

共 14 条

[1] LOCALIZATION OF THE GENE FOR FAMILIAL ADENOMATOUS POLYPOSIS ON CHROMOSOME-5 [J].

BODMER, WF ;

BAILEY, CJ ;

BODMER, J ;

BUSSEY, HJR ;

ELLIS, A ;

GORMAN, P ;

LUCIBELLO, FC ;

MURDAY, VA ;

RIDER, SH ;

SCAMBLER, P ;

SHEER, D ;

SOLOMON, E ;

SPURR, NK .

NATURE, 1987, 328 (6131) :614-616

[2] PREVALENCE OF RAS GENE-MUTATIONS IN HUMAN COLORECTAL CANCERS [J].

BOS, JL ;

FEARON, ER ;

HAMILTON, SR ;

VERLAANDEVRIES, M ;

VANBOOM, JH ;

VANDEREB, AJ ;

VOGELSTEIN, B .

NATURE, 1987, 327 (6120) :293-297

[3]

DURDEY P, 1987, LANCET, V2, P549

[4] MALIGNANT BLADDER TUMORS IN A MAN AND HIS 3 SONS [J].

FRAUMENI, JF ;

THOMAS, LB .

JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1967, 201 (07) :507-&

[5] POPULATION TRENDS IN CIGARETTE SMOKING AND BLADDER CANCER [J].

HOOVER, R ;

COLE, P .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 1971, 94 (05) :409-&

[6] MOLECULAR-GENETICS OF COLORECTAL-CARCINOMA [J].

KERR, IB .

BRITISH MEDICAL JOURNAL, 1989, 299 (6700) :637-638

[7] ABC OF CLINICAL GENETICS - GENETICS OF CANCER [J].

KINGSTON, HM .

BRITISH MEDICAL JOURNAL, 1989, 298 (6680) :1086-1089

[8] THE LYNCH SYNDROME-II AND UROLOGICAL MALIGNANCIES [J].

LYNCH, HT ;

ENS, JA ;

LYNCH, JF .

JOURNAL OF UROLOGY, 1990, 143 (01) :24-28

[9] HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER (LYNCH SYNDROME-I AND SYNDROME-II) - GENETICS, PATHOLOGY, NATURAL-HISTORY, AND CANCER CONTROL .1. [J].

LYNCH, HT ;

LANSPA, S ;

SMYRK, T ;

BOMAN, B ;

WATSON, P ;

LYNCH, J .

CANCER GENETICS AND CYTOGENETICS, 1991, 53 (02) :143-160

[10] NATURAL-HISTORY OF COLORECTAL-CANCER IN HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER (LYNCH SYNDROME-I AND SYNDROME-II) [J].

LYNCH, HT ;

WATSON, P ;

LANSPA, SJ ;

MARCUS, J ;

SMYRK, T ;

FITZGIBBONS, RJ ;

KRIEGLER, M ;

LYNCH, JF .

DISEASES OF THE COLON & RECTUM, 1988, 31 (06) :439-444

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