THERAPY OF RECURRENT INVASIVE URINARY-TRACT INFECTIONS OF MEN

被引：58

作者：

GLECKMAN, R ^{[1
]}

CROWLEY, M ^{[1
]}

NATSIOS, GA ^{[1
]}

机构：

[1] BOSTON UNIV,SCH MED,BOSTON,MA 02215

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 1979年 / 301卷 / 16期

关键词：

D O I：

10.1056/NEJM197910183011607

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

THERE has been new interest in the therapy of urinary-tract infections, and new treatment programs have evolved.1,2 Men with recurrent urinary-tract infections present a formidable therapeutic challenge.3,4 Presumably short courses of antibiotic therapy fail to eradicate foci of infection that are frequently associated with structural abnormalities within the prostatic and renal parenchyma. We undertook a randomized, double-blind, placebo-controlled study to determine whether an extended course of therapy for men with recurrent, invasive urinary-tract infections would be more effective than the conventional two-week course of therapy. We found that a six-week course of antimicrobial therapy resulted in fewer relapses than the. © 1979, Massachusetts Medical Society. All rights reserved.

引用

页码：878 / 880

页数：3

共 14 条

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[2] Kallenius G., Winberg J., Urinary tract infections treated with single dose of short-acting sulphonamide, Br Med J, 1, pp. 1175-1176, (1979)
[3] Lindemeyer R.I., Turck M., Petersdorf R.G., Factors determining the out-come of chemotherapy in infections of the urinary tract, Ann Intern Med, 58, pp. 201-216, (1963)
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[5] Brenner D.J., Farmer J.J., Hickman F.W., Taxonomic and Nomenclature Changes in Enterobacteriaceae, pp. 1-15, (1977)
[6] Thomas V., Shelokov A., Forland M., Antibody-coated bacteria in the urine and the site of urinary-tract infection, N Engl J Med, 290, pp. 588-590, (1974)
[7] Harding G., Marrie T.J., Ronald A.R., Et al., Urinary tract infection localization in women, JAMA, 240, pp. 1147-1150, (1978)
[8] Guidelines for Protocols of New Antimicrobial Efficacy in Urinary Tract Infections, (1975)
[9] Smith C.R., Baughman K.L., Edwards C.Q., Et al., Controlled comparison of amikacin and gentamicin, N Engl J Med, 296, pp. 349-353, (1977)
[10] Turck M., Petersdorf R.G., Optimal duration of treatment of chronic urinary tract infection, Ann Intern Med, 69, pp. 837-839, (1968)

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