STRUCTURAL INVESTIGATIONS OF INFLUENZA B VIRUS

被引:13
作者
MELLEMA, JE [1 ]
ANDREE, PJ [1 ]
KRYGSMAN, PCJ [1 ]
KROON, C [1 ]
RUIGROK, RWH [1 ]
CUSACK, S [1 ]
MILLER, A [1 ]
ZULAUF, M [1 ]
机构
[1] EUROPEAN MOLEC BIOL LAB, OUTSTN, GRENOBLE, FRANCE
关键词
D O I
10.1016/0022-2836(81)90521-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Purified preparations of influenza B/Hong Kong/5/72 virus were characterized by hydrodynamic measurements, EM and small-angle neutron scattering. As judged by these techniques, the preparations are highly monodisperse, the virus particles being spherical and of MW .apprx. 200 .times. 106. The lipid bilayer is located at a radius of 425 .ANG. and its MW is estimated to be 60 .times. 106, constituting .apprx. 30% of the total virus mass. The external radius is .apprx. 580 .ANG.
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页码:329 / 336
页数:8
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