SELECTIVE KILLING OF A SINGLE CANCEROUS T24 CELL WITH TIO2 SEMICONDUCTING MICROELECTRODE UNDER IRRADIATION

被引：44

作者：

SAKAI, H

BABA, R

HASHIMOTO, K

KUBOTA, Y

FUJISHIMA, A

机构：

[1] UNIV TOKYO,FAC ENGN,DEPT APPL CHEM,BUNKYO KU,TOKYO 113,JAPAN

[2] YOKOHAMA CITY UNIV,SCH MED,KANAZAWA KU,YOKOHAMA,KANAGAWA 236,JAPAN

来源：

CHEMISTRY LETTERS | 1995年 / 03期

关键词：

D O I：

10.1246/cl.1995.185

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A titanium dioxide (TiO2) microelectrode has been applied for selective photo-killing of a single cancerous T24 cell. The anodically polarized TiO2 microelectrode effectively inactivated the T24 cell while in contact and under UV light irradiation; however, the cell was not killed when the microelectrode was located 10 mu m away from the cell surface. Based on these results we concluded that the photogenerated holes and/or active oxygen species with short diffusion length are responsible for the cell death process.

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页码：185 / 186

页数：2

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