INHIBITION OF DARK REPAIR OF ULTRAVIOLET DAMAGE IN DNA BY CAFFEINE AND 8-CHLOROCAFFEINE . KINETICS OF INHIBITION

被引：22

作者：

LUMB, JR

SIDEROPOULOS, AS

SHANKEL, DM

机构：

[1] Department of Microbiology, The University of Kansas, Lawrence, Kansas

[2] M.R.C. Mutagenesis Unit, University of Edinburgh, Edinburgh, 9, West Mains Road

来源：

MOLECULAR AND GENERAL GENETICS | 1968年 / 102卷 / 02期

关键词：

D O I：

10.1007/BF01789137

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The inhibition of dark repair by caffeine and 8-chlorocaffeine was investigated by a cellular enzyme kinetics system. The results suggest that the caffeine and 8-chlorocaffeine act by inhibiting the excision enzyme of the dark repair system. © 1968 Springer-Verlag.

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页码：108 / +

页数：1

相关论文

共 11 条

[1] RELEASE OF ULTRAVIOLET LIGHT-INDUCED THYMINE DIMERS FROM DNA IN E. COLI K-12 [J].

BOYCE, RP ;

HOWARDFLANDERS, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1964, 51 (02) :293-&

[2]

DONESON I, 1963, J BACTERIOL, V87, P61

[3] ENHANCEMENT OF ULTRAVIOLET-INDUCED MUTATION IN BACTERIA BY CAFFEINE [J].

LIEB, M .

ZEITSCHRIFT FUR VERERBUNGSLEHRE, 1961, 92 (04) :416-&

[4] EVIDENCE FOR REPAIR-REPLICATION OF ULTRAVIOLET DAMAGED DNA IN BACTERIA [J].

PETTIJOHN, DE ;

HANAWALT, P .

JOURNAL OF MOLECULAR BIOLOGY, 1964, 9 (02) :395-&

[5]

RUPERT CS, 1958, FED PROC, V17, P301

[6] RELATION OF REPAIR OF DAMAGE INDUCED BY A MONOFUNCTIONAL ALKYLATING AGENT TO REPAIR OF DAMAGE INDUCED BY ULTRAVIOLET LIGHT IN BACILLUS SUBTILIS [J].

SEARASHI, T ;

STRAUSS, B .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1965, 20 (06) :680-&

[7] DISAPPEARANCE OF THYMINE DIMERS FROM DNA - ERROR-CORRECTING MECHANISM [J].

SETLOW, RB ;

CARRIER, WL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1964, 51 (02) :226-&

[8] PYRIMIDINE DIMERS IN ULTRAVIOLET-IRRADIATED DNAS [J].

SETLOW, RB ;

CARRIER, WL .

JOURNAL OF MOLECULAR BIOLOGY, 1966, 17 (01) :237-&

[9] MUTATIONAL SYNERGISM OF ULTRAVIOLET LIGHT AND CAFFEINE IN ESCHERICHIA COLI [J].

SHANKEL, DM .

JOURNAL OF BACTERIOLOGY, 1962, 84 (03) :410-&

[10] MODIFICATION OF MUTAGENESIS INITIATED BY ULTRAVIOLET LIGHT THROUGH POSTTREATMENT OF BACTERIA WITH BASIC DYES [J].

WITKIN, EM .

JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY, 1961, 58 :135-&