ENHANCEMENT BY HYPOPHYSEAL HORMONES ON MALIGNANT TRANSFORMATION OF TRANSPLANTED HYPERPLASTIC NODULES OF MOUSE MAMMARY GLAND

被引:11
作者
DUX, A
MUHLBOCK, O
机构
[1] Biological Department, Antoni van Leeuwenhoekhuis, The Netherlands Cancer Institute, Amsterdam
关键词
D O I
10.1016/0014-2964(69)90066-8
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The first step in the development of mammary carcinoma in mice is the formation of a hyperplastic nodule. Hormonal and viral factors are instrumental in the formation of the nodule. It is shown that transplanted nodules transformed earlier into a carcinoma when a hypophyseal isograft next to the transplant was present. The stronger hormonal stimulation accelerates the tumour formation from a hyperplastic nodule. © 1969.
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页码:191 / &
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