EFFECTS OF RANITIDINE AND METOCLOPRAMIDE ON GASTRIC FLUID PH AND VOLUME IN CHILDREN

被引：12

作者：

CHRISTENSEN, S

FARROWGILLESPIE, A

LERMAN, DJ

机构：

[1] UNIV TORONTO,HOSP SICK CHILDREN,DEPT ANAESTHESIA,555 UNIV AVE,TORONTO M5G 1X8,ONTARIO,CANADA

[2] UNIV TORONTO,HOSP SICK CHILDREN,RES INST,TORONTO M5G 1X8,ONTARIO,CANADA

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1990年 / 65卷 / 04期

关键词：

Anaesthesia: paediatric; Gastrointestinal tract: gastric fluid volume; gastric pH; Premedication:; metoclopramide; ranitidine;

D O I：

10.1093/bja/65.4.456

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

To determine the effects of ranitidine and metoclopramide on gastric fluid in children, 40 healthy children (aged 2-8 yr) were allocated randomly to groups of 10 to receive one of four oral premedications 4 h before surgery: no premedication, metoclopramide 0.1 mg kg-1 ranitidine 2 mg kg-1 and metoclopramide 0.1 mg kg-1 with ranitidine 2mg kg-1. After tracheal intubation, gastric fluid was aspirated and analysed for pH and total fluid volume. Ranitidine, with or without metoclopramide, increased gastric fluid pH significantly compared with control (P < 0.05). Gastric fluid volume did not change significantly. © 1990 Copyright: 1990 British Journal of Anaesthesia.

引用

页码：456 / 460

页数：5

共 28 条

[1] INACCURACY OF PREANESTHETIC GASTRIC INTUBATION FOR EMPTYING LIQUID STOMACH CONTENTS [J].