IA ANTIGEN EXPRESSION ON THE DEVELOPING MOUSE EMBRYO AND PLACENTA

被引：49

作者：

JENKINSON, EJ

SEARLE, RF

机构：

[1] Reproductive Immunology Group, Department of Pathology, The Medical School, Bristol

来源：

JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 1979年 / 1卷 / 01期

关键词：

D O I：

10.1016/0165-0378(79)90024-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The expression of I region controlled antigens on the mouse embryo and placenta has been investigated using immuno-peroxidase labelling and a mixed haemadsorption assay. The results indicate that Ia antigens are absent from selected pre- and post-implantation embryonic and trophoblastic tissues and from the trophoblast of the definitive placenta. In contrast, cells derived from the peri-placental maternal decidual tissues are Ia antigen-positive. The findings are discussed in relation to the allograft status of the conceptus and the identity and functional significance of the Ia-bearing maternal cells at the focto-maternal interface. © 1979.

引用

页码：3 / 10

页数：8

共 29 条

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