ULTRASTRUCTURE OF TELANGIECTATIC OSTEOSARCOMA

被引：12

作者：

ROESSNER, A ^{[1
]}

HOBIK, HP ^{[1
]}

IMMENKAMP, M ^{[1
]}

GRUNDMANN, E ^{[1
]}

机构：

[1] UNIV MUNSTER,ORTHOPAED CLIN,D-4400 MUNSTER,FED REP GER

来源：

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY | 1979年 / 95卷 / 02期

关键词：

Electron microscopy; Histogenesis; Telangiectatic osteosarcoma;

D O I：

10.1007/BF00401013

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Recent investigations have shown that telangiectatic osteosarcoma has a poorer prognosis than other osteosarcomas. To elucidate the histogenesis of TOS two cases were investigated on the electron microscopic level. The results show that besides anaplastic, osteoblast-like, and fibroblast-like tumor cells angiosarcomatous components can be observed in this malignant bone tumor, which are characterized by endothelial cells with pinocytotic vesicles, tight intercellular junctions, fine fibrils, and so-called Weibel-Palade bodies in their cytoplasm. From these results, it is concluded that telangiectatic osteosarcoma is derived from multipotent mesenchymal cells with potential differentiation into various directions, such as osteoblast-like cells, endothelial cells, and fibroblast-like cells. © 1979 Springer-Verlag.

引用

页码：197 / 207

页数：11

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