CHIRALITY AND ITS IMPORTANCE IN DRUG DEVELOPMENT - AN ANALYTICAL CHEMISTS PERSPECTIVE

被引：6

作者：

FELL, AF

LEY, GW

机构：

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 1991年 / 19卷 / 02期

关键词：

D O I：

10.1042/bst0190454

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：454 / 456

页数：3

共 19 条

[1] DIRECT OPTICAL RESOLUTION OF A SERIES OF PHARMACOLOGICALLY ACTIVE RACEMIC SULFOXIDES BY HIGH-PERFORMANCE LIQUID AFFINITY-CHROMATOGRAPHY [J].

ALLENMARK, S ;

BOMGREN, B ;

BOREN, H ;

LAGERSTROM, PO .

ANALYTICAL BIOCHEMISTRY, 1984, 136 (02) :293-297

[2]

Allenmark S. G., 1988, CHROMATOGRAPHIC ENAN

[3] SEPARATION OF DRUG STEREOISOMERS BY THE FORMATION OF BETA-CYCLODEXTRIN INCLUSION COMPLEXES [J].

ARMSTRONG, DW ;

WARD, TJ ;

ARMSTRONG, RD ;

BEESLEY, TE .

SCIENCE, 1986, 232 (4754) :1132-1135

[4]

DAEPPEN R, 1986, J CHROMATOGR, V373, P1

[5]

DALGLIESH CE, 1952, J CHEM SOC, V137, P3940

[6] COMPUTER-AIDED OPTIMIZATION OF DRUG ENANTIOMER SEPARATION IN CHIRAL HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

FELL, AF ;

NOCTOR, TAG ;

MAMA, JE ;

CLARK, BJ .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1988, 434 (02) :377-384

[7] CHROMATOGRAPHIC RESOLUTION OF RACEMATES ON CHIRAL STATIONARY PHASES .1. INFLUENCE OF THE SUPRAMOLECULAR STRUCTURE OF CELLULOSE TRIACETATE [J].

FRANCOTTE, E ;

WOLF, RM ;

LOHMANN, D ;

MUELLER, R .

JOURNAL OF CHROMATOGRAPHY, 1985, 347 (01) :25-37

[8] SEPARATION OF ISOMERIC COMPOUNDS AS CYCLODEXTRIN INCLUSION COMPLEXES ON A CYANOPROPYLSILICA STATIONARY PHASE [J].

GAZDAG, M ;

SZEPESI, G ;

HUSZAR, L .

JOURNAL OF CHROMATOGRAPHY, 1986, 371 :227-234

[9] RELATIONSHIP BETWEEN ENANTIOSELECTIVITY AND SOLUTE STRUCTURE ON A CHIRAL ALPHA-1-ACID GLYCOPROTEIN COLUMN [J].

HERMANSSON, J ;

STROM, K ;

SANDBERG, R .

CHROMATOGRAPHIA, 1987, 24 :520-526

[10] CHIROPTICAL DETECTION - NOVEL POSSIBILITIES OF ITS APPLICATION TO ENANTIOMERS [J].

MANNSCHRECK, A ;

ANDERT, D ;

EIGLSPERGER, A ;

GMAHL, E ;

BUCHNER, H .

CHROMATOGRAPHIA, 1988, 25 (03) :182-188

← 1 2 →