NEAMPHINE, A SULFUR-CONTAINING AROMATIC HETEROCYCLE ISOLATED FROM THE MARINE SPONGE NEAMPHIUS-HUXLEYI

被引：12

作者：

DESILVA, ED

RACOK, JS

ANDERSEN, RJ

ALLEN, TM

BRINEN, LS

CLARDY, J

机构：

[1] UNIV BRITISH COLUMBIA,DEPT CHEM,VANCOUVER V6T 1W5,BC,CANADA

[2] UNIV BRITISH COLUMBIA,DEPT OCEANOG,VANCOUVER V6T 1W5,BC,CANADA

[3] UNIV ALBERTA,DEPT PHARMACOL,EDMONTON T6G 2H7,ALBERTA,CANADA

[4] CORNELL UNIV,DEPT CHEM,BAKER LAB,ITHACA,NY 14853

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 24期

基金：

加拿大自然科学与工程研究理事会;

关键词：

SPONGE; SULFUR; NITROGEN; HETEROCYCLE; CYTOTOXIC;

D O I：

10.1016/0040-4039(91)85064-C

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The structure of neamphine (1), a cytotoxic metabolite of the marine sponge Neamphius huxleyi, has been solved by single crystal x-ray diffraction analysis. Neamphine (1) represents the first example, either from nature or synthesis, of the imidazo[4,5-e]-1,2-thiazine ring system.

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页码：2707 / 2710

页数：4

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