ALTERATIONS IN SENSITIVITY TO EFFECTORS OF RAT LIVER ACETYL-COA CARBOXYLASE FOLLOWING TRYPSIN TREATMENT

被引：18

作者：

IRITANI, N

NAKANISHI, S

NUMA, S

机构：

[1] Department of Medical Chemistry Kyoto University Faculty of Medicine, Kyoto

来源：

LIFE SCIENCES PART 1 PHYSIOLOGY AND PHARMACOLOGY AND PART 2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY | 1969年 / 8卷 / 22P2期

关键词：

D O I：

10.1016/0024-3205(69)90170-2

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

1. 1. Highly purified acetyl-CoA carboxylase from rat liver, when treated with trypsin, exhibited considerable activity even in the absence of citrate. 2. 2. The trypsin-treated enzyme was less sensitive to an inhibitor, palmityl-CoA, than control enzyme. 3. 3. Sucrose density gradient centrifugation of partially purified carboxylase revealed that the sedimentation coefficient of the enzyme was also altered by trypsin treatment in correlation with the changes in the sensitivity to effectors. © 1969.

引用

页码：1157 / +

页数：1

共 13 条

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