EFFECT OF REPEATED ADMINISTRATION OF NOVEL STRESSORS ON CENTRAL BETA-ADRENOCEPTORS

被引：16

作者：

ARESO, MP

FRAZER, A

机构：

[1] UNIV PENN, SCH MED, DEPT PHARMACOL, PHILADELPHIA, PA 19104 USA

[2] UNIV PENN, SCH MED, DEPT PSYCHIAT, PHILADELPHIA, PA 19104 USA

来源：

JOURNAL OF NEURAL TRANSMISSION-GENERAL SECTION | 1991年 / 86卷 / 03期

关键词：

STRESS; BETA-ADRENOCEPTORS; AMYGDALA;

D O I：

10.1007/BF01250709

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Subtypes of beta adrenoceptors were measured in 17 different areas of brain in rats exposed for 12 days to novel stressors. Mild stress such as individual housing and handling caused no change in beta1 and beta2 adrenoceptors in comparison with that measured in rats that were group housed and never handled. Exposure of rats to more severe stressors did reduce significantly the binding of I-125-iodopindolol (I-125-IPIN) to beta1 adrenoceptors, but not beta2 adrenoceptors, only in the lateral and basolateral nuclei of the amygdala.

引用

页码：229 / 235

页数：7

共 36 条

[1] SYSTEMIC NALOXONE ADMINISTRATION POTENTIATES LOCUS COERULEUS NORADRENERGIC NEURONAL-ACTIVITY UNDER STRESSFUL BUT NOT NON-STRESSFUL CONDITIONS [J].