NEW METHOD FOR THE PREPARATION OF L-GULOSE FROM D-MANNOSE - SYNTHETIC STUDY ON THE SUGAR MOIETY OF BLEOMYCIN

被引：16

作者：

OSHITARI, T ^{[1
]}

TOMITA, M ^{[1
]}

KOBAYASHI, S ^{[1
]}

机构：

[1] SAGAMI CHE RES CTR,SAGAMIHARA 229,KANAGAWA,JAPAN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 35期

关键词：

D O I：

10.1016/S0040-4039(00)78254-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

L-Gulose, a key building block of the carbohydrate moiety of antitumor antibiotic bleomycins, is prepared from D-mannose by the inversion at C-5.

引用

页码：6493 / 6494

页数：2

共 8 条

[1]

FISHER E, 1891, CHEM BER, V24, P521

[2]

ISBELL HS, METHODS CARBOHYDR CH, V1, P135

[3] SYNTHESIS OF THE CARBOHYDRATE MOIETY OF BLEOMYCIN - 1,3,4,6-TETRA-O-SUBSTITUTED L-GULOSE DERIVATIVES [J].

KATANO, K ;

CHANG, PI ;

MILLAR, A ;

POZSGAY, V ;

MINSTER, DK ;

OHGI, T ;

HECHT, SM .

JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (26) :5807-5815

[4] AN EFFICIENT O-MONOALKYLATION OF DIMETHYL L-TARTRATE VIA O-STANNYLENE ACETAL WITH ALKYL-HALIDES IN THE PRESENCE OF CESIUM FLUORIDE [J].

NAGASHIMA, N ;

OHNO, M .

CHEMISTRY LETTERS, 1987, (01) :141-144

[5]

OTSUKA M, 1992, HETEROCYCLES, V33, P27

[6] MERCURICYCLIZATION IN CARBOHYDRATE-CHEMISTRY - A HIGHLY STEREOSELECTIVE ROUTE TO ALPHA-D-C-GLUCOPYRANOSYL DERIVATIVES [J].

POUGNY, JR ;

NASSR, MAM ;

SINAY, P .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1981, (08) :375-376

[7] MECHANISMS OF BLEOMYCIN-INDUCED DNA-DEGRADATION [J].

STUBBE, J ;

KOZARICH, JW .

CHEMICAL REVIEWS, 1987, 87 (05) :1107-1136

[8]

SUGIURA Y, 1983, J BIOL CHEM, V258, P1328

← 1 →