EXTRACELLULAR PROTONS ACIDIFY OSTEOCLASTS, REDUCE CYTOSOLIC CALCIUM, AND PROMOTE EXPRESSION OF CELL-MATRIX ATTACHMENT STRUCTURES

被引：130

作者：

TETI, A

BLAIR, HC

SCHLESINGER, P

GRANO, M

ZAMBONINZALLONE, A

KAHN, AJ

TEITELBAUM, SL

HRUSKA, KA

机构：

[1] WASHINGTON UNIV,JEWISH HOSP ST LOUIS,MED CTR,DEPT PATHOL,ST LOUIS,MO 63110

[2] WASHINGTON UNIV,JEWISH HOSP ST LOUIS,SCH DENT MED,DEPT BIOL SCI,ST LOUIS,MO 63110

[3] UNIV BARI,INST HUMAN ANAT,I-70124 BARI,ITALY

[4] ST LOUIS UNIV,MED CTR,PEDIAT RES INST,ST LOUIS,MO 63110

[5] SHRINERS HOSP CRIPPLED CHILDREN,ST LOUIS,MO 63131

[6] WASHINGTON UNIV,JEWISH HOSP ST LOUIS,MED CTR,DEPT MED,DIV RENAL,ST LOUIS,MO 63110

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1989年 / 84卷 / 03期

关键词：

D O I：

10.1172/JCI114235

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：773 / 780

页数：8

共 35 条

[1]

AKISAKA T, 1988, J BONE MINER RES, V3, P19

[2] HUMORAL AND IONIC REGULATION OF OSTEOCLAST ACIDITY [J].

ANDERSON, RE ;

WOODBURY, DM ;

JEE, WSS .

CALCIFIED TISSUE INTERNATIONAL, 1986, 39 (04) :252-258

[3] EFFECT OF PH ON BONE-RESORPTION BY RAT OSTEOCLASTS INVITRO [J].

ARNETT, TR ;

DEMPSTER, DW .

ENDOCRINOLOGY, 1986, 119 (01) :119-124

[4] EXOCYTOSIS - CONTROL BY CALCIUM AND OTHER FACTORS [J].

BAKER, PF ;

KNIGHT, DE .

BRITISH MEDICAL BULLETIN, 1986, 42 (04) :399-404

[5]

BAKER PF, 1986, ION CHANNELS NEURAL, P177

[6] CELL-MEDIATED EXTRACELLULAR ACIDIFICATION AND BONE-RESORPTION - EVIDENCE FOR A LOW PH IN RESORBING LACUNAE AND LOCALIZATION OF A 100-KD LYSOSOMAL MEMBRANE-PROTEIN AT THE OSTEOCLAST RUFFLED BORDER [J].

BARON, R ;

NEFF, L ;

LOUVARD, D ;

COURTOY, PJ .

JOURNAL OF CELL BIOLOGY, 1985, 101 (06) :2210-2222

[7] ISOLATED OSTEOCLASTS RESORB THE ORGANIC AND INORGANIC COMPONENTS OF BONE [J].

BLAIR, HC ;

KAHN, AJ ;

CROUCH, EC ;

JEFFREY, JJ ;

TEITELBAUM, SL .

JOURNAL OF CELL BIOLOGY, 1986, 102 (04) :1164-1172

[8]

BLAIR HC, IN PRESS SCIENCE WAS

[9] KINETIC-ANALYSIS OF F-ACTIN DEPOLYMERIZATION IN THE PRESENCE OF PLATELET GELSOLIN AND GELSOLIN ACTIN COMPLEXES [J].

BRYAN, J ;

COLUCCIO, LM .

JOURNAL OF CELL BIOLOGY, 1985, 101 (04) :1236-1244

[10] CELLULAR CONTRIBUTION TO PH-MEDIATED CALCIUM FLUX IN NEONATAL MOUSE CALVARIAE [J].

BUSHINSKY, DA ;

GOLDRING, JM ;

COE, FL .

AMERICAN JOURNAL OF PHYSIOLOGY, 1985, 248 (06) :F785-F789

← 1 2 3 4 →