PARENTERAL-NUTRITION IN BONE-MARROW TRANSPLANTATION

被引：28

作者：

LOUGH, M

WATKINS, R

CAMPBELL, M

CARR, K

BURNETT, A

SHENKIN, A

机构：

[1] Department of Pathological Biochemistry, Royal Infirmary, Glasgow

[2] Department of Haematology Royal Infirmary, Glasgow

[3] Department of Dietetics, Royal Infirmary, Glasgow

来源：

CLINICAL NUTRITION | 1990年 / 9卷 / 02期

关键词：

D O I：

10.1016/0261-5614(90)90060-6

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Twenty-nine patients undergoing bone marrow transplantation (BMT) were randomised prospectively to evaluate the effect of parenteral nutrition (TPN) on morbidity and mortality. Fourteen patients received a standard regimen of TPN for 10 ± 4 days (mean ± SD). All patients had free access to oral diet, which was significantly reduced compared to pre-transplant intake. In the TPN group, serum bilirubin by day 14 and serum bilirubin and gamma glutamyl transferase by day 21 were significantly higher than in the controls (p < 0.05). These differences probably reflect the higher incidence of serious pyrexia (T > 38.5' C) and blood culture positive rates in the TPN group. Weight loss in the control group was significantly greater than that of the TPN group (p < 0.05). TPN did not affect time to grafting or incidence of graft-versus-host disease. The use of TPN in the nutritional support of patients in small BMT units requires careful consideration. © 1990.

引用

页码：97 / 101

页数：5

共 22 条

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