EFFECT OF BENZOIC-ACID ON GLYCOLYTIC METABOLITE LEVELS AND INTRACELLULAR PH IN SACCHAROMYCES-CEREVISIAE

被引:48
作者
WARTH, AD [1 ]
NICKERSON, KW [1 ]
机构
[1] CSIRO,DIV FOOD PROC,N RYDE,NSW 2113,AUSTRALIA
关键词
D O I
10.1128/AEM.57.12.3415-3417.1991
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Low concentrations of benzoic acid stimulated fermentation rates in Saccharomyces cerevisiae. At concentrations near the maximum permitting growth, there was inhibition of fermentation, lowered ATP and intracellular pH, and relatively greater accumulation of benzoate. Changes in the levels of glycolytic intermediates suggested that fermentation was inhibited as a result of high ATP usage rather than of lowered intracellular pH. Specific inhibition of phosphofructokinase or of several other glycolytic enzymes was not observed.
引用
收藏
页码:3415 / 3417
页数:3
相关论文
共 11 条
[1]  
CERIACY M, 1979, J BACTERIOL, V2139, P152
[2]   CONCENTRATIONS OF INTERMEDIARY METABOLITES IN YEAST [J].
GANCEDO, JM ;
GANCEDO, C .
BIOCHIMIE, 1973, 55 (02) :205-211
[3]   STUDIES ON THE MECHANISM OF THE ANTI-FUNGAL ACTION OF BENZOATE [J].
KREBS, HA ;
WIGGINS, D ;
STUBBS, M ;
SOLS, A ;
BEDOYA, F .
BIOCHEMICAL JOURNAL, 1983, 214 (03) :657-663
[4]  
Sols A., 1971, YEASTS, V2, P271
[5]   MECHANISM OF RESISTANCE OF SACCHAROMYCES-BAILII TO BENZOIC, SORBIC AND OTHER WEAK ACIDS USED AS FOOD PRESERVATIVES [J].
WARTH, AD .
JOURNAL OF APPLIED BACTERIOLOGY, 1977, 43 (02) :215-230
[6]  
WARTH AD, 1985, J FOOD PROTECT, V48, P564, DOI 10.4315/0362-028X-48.7.564
[10]  
WARTH AD, 1989, J GEN MICROBIOL, V135, P1383